Loading...
Chemical structure of MI-1061 TFA

GC62598

MI-1061 TFA

MI-1061 TFA is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4·4 nM; Ki=0·16 nM)· MI-1061 TFA potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice· Anti-tumor activity

ChemicalCAS1410737-35-7MW696.47FormulaC32H27Cl2F4N3O6
CAS number
1410737-35-7
Molecular weight
696.47
Formula
C32H27Cl2F4N3O6
Solubility
DMSO ： 120 mg/mL (172·30 mM; Need ultrasonic)
InChIKey
YVEFTHDIYIEZGS-FLLZXHAKSA-N
Catalogue number
GC62598
Brand
GLPBIO
Computed properties PubChem CID 155981982 · TPSA 145 Ų · H-bond donors 5 · H-bond acceptors 11
TPSA
145 Ų
H-bond donors
5
H-bond acceptors
11
Rotatable bonds
4
Heavy atoms
47

SMILES C1CCC2(CC1)[C@@]3([C@H]([C@@H](N2)C(=O)NC4=CC=C(C=C4)C(=O)O)C5=C(C(=CC=C5)Cl)F)C6=C(C=C(C=C6)Cl)NC3=O.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 155981982), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.