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Chemical structure of NAcM-OPT

GC64989

NAcM-OPT

Also known as 1-benzyl-1-(1-butylpiperidin-4-yl)-3-(3,4-dichlorophenyl)urea

NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction

ChemicalCAS2089293-61-6MW434.4FormulaC23H29Cl2N3O
CAS number
2089293-61-6
Molecular weight
434.4
Formula
C23H29Cl2N3O
Solubility
DMSO : 125 mg/mL (287·75 mM; Need ultrasonic)
InChIKey
VPHJABWIKCBGMC-UHFFFAOYSA-N
Catalogue number
GC64989
Brand
GLPBIO
Computed properties PubChem CID 126711307 · XLogP 5.7 · TPSA 35.6 Ų · H-bond donors 1
XLogP
5.7
TPSA
35.6 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
7
Heavy atoms
29

SMILES CCCCN1CCC(CC1)N(CC2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)Cl)Cl

Computed descriptors from PubChem (CID 126711307), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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