GC61621
NAZ2329
NAZ2329, the first cell-permeable inhibitor of R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), allosterically and preferentially inhibits PTPRZ (IC50=7·5 ?M for hPTPRZ1) and PTPRG (IC50=4·8 ?M for hPTPRG) over other PTPs· NAZ2329 binds to the active D1 domain and more potently inhibits PTPRZ-D1 fragment (IC50 of 1·1 ?M) than the whole intracellular (D1?+?D2) fragment (IC50 of 7·5 ?M)· NAZ2329 can effectively inhibit tumor growth of the glioblastoma cells and suppress stem cell-like properties
ChemicalMW501.56FormulaC21H18F3NO4S3
- CAS number
- —
- Molecular weight
- 501.56
- Formula
- C21H18F3NO4S3
- Solubility
- DMSO： 100 mg/mL (199·38 mM)
- Catalogue number
- GC61621
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il