GC64974
FT113
Also known as [4-(6-fluoro-1,3-benzoxazol-2-yl)phenyl]-[4-(1-hydroxycyclopropanecarbonyl)piperazin-1-yl]methanone
FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme· In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM)· FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo
ChemicalCAS1630808-89-7MW409.41FormulaC22H20FN3O4
- CAS number
- 1630808-89-7
- Molecular weight
- 409.41
- Formula
- C22H20FN3O4
- Solubility
- DMSO ： 62·5 mg/mL (152·66 mM; Need ultrasonic)
- InChIKey
- DSTWHRGOCUOKDE-UHFFFAOYSA-N
- Catalogue number
- GC64974
- Brand
- GLPBIO
Computed properties PubChem CID 118621601 · XLogP 1.9 · TPSA 86.9 Ų · H-bond donors 1
- XLogP
- 1.9
- TPSA
- 86.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 30
SMILES C1CC1(C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C4=NC5=C(O4)C=C(C=C5)F)O
Computed descriptors from PubChem (CID 118621601), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il