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Chemical structure of FT827

GC32917

FT827

Also known as N-[2-[4-[4-hydroxy-4-[(1-methyl-4-oxopyrazolo[5,4-d]pyrimidin-5-yl)methyl]piperidine-1-carbonyl]phenyl]phenyl]ethenesulfonamide

FT827 is a selective and covalent ubiquitin-specific protease 7 (USP7) inhibitor (Ki=4·2 ?M)· FT827 binds to the USP7 catalytic domain (USP7CD; residues 208-560) with an apparent Kd value of 7·8 ?M

ChemicalCAS1959537-86-0MW548.61FormulaC27H28N6O5S
CAS number
1959537-86-0
Molecular weight
548.61
Formula
C27H28N6O5S
Solubility
DMSO ： 125 mg/mL (227·85 mM)
InChIKey
GFNJQQBUZURQMA-UHFFFAOYSA-N
Catalogue number
GC32917
Brand
GLPBIO
Computed properties PubChem CID 121435663 · XLogP 1.5 · TPSA 146 Ų · H-bond donors 2
XLogP
1.5
TPSA
146 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
39

SMILES CN1C2=C(C=N1)C(=O)N(C=N2)CC3(CCN(CC3)C(=O)C4=CC=C(C=C4)C5=CC=CC=C5NS(=O)(=O)C=C)O

Computed descriptors from PubChem (CID 121435663), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.