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Chemical structure of CSF1R-IN-2

GC64961

CSF1R-IN-2

Also known as (11S)-16-amino-2-ethyl-6-fluoro-11-methyl-14-oxo-10-oxa-2,13,17,18,21-pentazatetracyclo[13.5.2.04,9.018,22]docosa-1(21),4(9),5,7,15(22),16,19-heptaene-5-carbonitrile

CSF1R-IN-2 (compound 5) is an oral-active inhibitor of SRC, MET and c-FMS, with IC50 values of 0·12 nM, 0·14 nM and 0·76 nM for SRC, MET and c-FMS respectively

ChemicalCAS2271119-26-5MW409.42FormulaC20H20FN7O2
CAS number
2271119-26-5
Molecular weight
409.42
Formula
C20H20FN7O2
Solubility
DMSO ： 25 mg/mL (61·06 mM; Need ultrasonic)
InChIKey
UUDPUQDMSHQSKH-NSHDSACASA-N
Catalogue number
GC64961
Brand
GLPBIO
Computed properties PubChem CID 137455315 · XLogP 2.1 · TPSA 122 Ų · H-bond donors 2
XLogP
2.1
TPSA
122 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
1
Heavy atoms
30

SMILES CCN1CC2=C(C=CC(=C2C#N)F)O[C@H](CNC(=O)C3=C4N=C1C=CN4N=C3N)C

Computed descriptors from PubChem (CID 137455315), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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