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Chemical structure of GSK963

GC64951

GSK963

Also known as 2,2-dimethyl-1-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one

GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM

ChemicalCAS2049868-46-2MW230.31FormulaC14H18N2O
CAS number
2049868-46-2
Molecular weight
230.31
Formula
C14H18N2O
Solubility
DMSO ： 25 mg/mL (108·55 mM; Need ultrasonic)
InChIKey
NJQVSLWJBLPTMD-LBPRGKRZSA-N
Catalogue number
GC64951
Brand
GLPBIO
Computed properties PubChem CID 122703613 · XLogP 2.1 · TPSA 32.7 Ų · H-bond donors 0
XLogP
2.1
TPSA
32.7 Ų
H-bond donors
0
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
17

SMILES CC(C)(C)C(=O)N1[C@@H](CC=N1)C2=CC=CC=C2

Computed descriptors from PubChem (CID 122703613), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.