Loading...
Chemical structure of SHMT-IN-1

GC64890

SHMT-IN-1

Also known as 6-amino-4-cyclobutyl-4-(3,5-dichlorophenyl)-3-methyl-2H-pyrano[2,3-c]pyrazole-5-carbonitrile

SHMT-IN-1 (compound (±)-46) is a potent inhibitor of plasmodial serine hydroxymethyltransferase (SHMT)· SHMT-IN-1 has antitumor activity

ChemicalCAS1508286-18-7MW375.25FormulaC18H16Cl2N4O
CAS number
1508286-18-7
Molecular weight
375.25
Formula
C18H16Cl2N4O
Solubility
DMSO ： 250 mg/mL (666·22 mM; Need ultrasonic)
InChIKey
SPNNZCKKJSFKKB-UHFFFAOYSA-N
Catalogue number
GC64890
Brand
GLPBIO
Computed properties PubChem CID 122535411 · XLogP 5.2 · TPSA 87.7 Ų · H-bond donors 2
XLogP
5.2
TPSA
87.7 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
25

SMILES CC1=C2C(=NN1)OC(=C(C2(C3CCC3)C4=CC(=CC(=C4)Cl)Cl)C#N)N

Computed descriptors from PubChem (CID 122535411), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.