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Chemical structure of SHP099

GC44887

SHP099

Also known as 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine

SHP099 is an orally bioavailable inhibitor of SHP2, a non-receptor protein tyrosine phosphatase (IC50 = 71 nM)

ChemicalCAS1801747-42-1MW352.3FormulaC16H19Cl2N5
CAS number
1801747-42-1
Molecular weight
352.3
Formula
C16H19Cl2N5
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,DMSO：PBS(pH 7·2) (1：2)： 0·33 mg/ml,Ethanol： 10 mg/ml
InChIKey
YGUFCDOEKKVKJK-UHFFFAOYSA-N
Catalogue number
GC44887
Brand
GLPBIO
Computed properties PubChem CID 118238298 · XLogP 2.6 · TPSA 81.1 Ų · H-bond donors 2
XLogP
2.6
TPSA
81.1 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
23

SMILES CC1(CCN(CC1)C2=CN=C(C(=N2)N)C3=C(C(=CC=C3)Cl)Cl)N

Computed descriptors from PubChem (CID 118238298), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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