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Chemical structure of Lenalidomide-PEG1-azide

GC64867

Lenalidomide-PEG1-azide

Also known as 2-(2-azidoethoxy)-N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]acetamide

Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate· Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker·?Lenalidomide-PEG1-azide?can be used to design a PROTAC BRD4 Degrader-2

ChemicalCAS2185795-67-7MW386.36FormulaC17H18N6O5
CAS number
2185795-67-7
Molecular weight
386.36
Formula
C17H18N6O5
Solubility
DMSO : 100 mg/mL (258·83 mM; Need ultrasonic)
InChIKey
GGIQROQPJRHRQW-UHFFFAOYSA-N
Catalogue number
GC64867
Brand
GLPBIO
Computed properties PubChem CID 141507299 · XLogP 0.1 · TPSA 119 Ų · H-bond donors 2
XLogP
0.1
TPSA
119 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
28

SMILES C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3NC(=O)COCCN=[N+]=[N-]

Computed descriptors from PubChem (CID 141507299), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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