GC64834
Glucosylceramide synthase-IN-1
Also known as 4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-2-[4-(2-hydroxypropan-2-yl)phenyl]-3H-pyrrolo[3,4-c]pyridin-1-one
Glucosylceramide synthase-IN-1 (T-036) a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 31 nM and 51 nM for human GCS and mouse GCS, respectively
ChemicalCAS2601393-20-6MW460.42FormulaC24H20F4N2O3
- CAS number
- 2601393-20-6
- Molecular weight
- 460.42
- Formula
- C24H20F4N2O3
- Solubility
- DMSO ： 100 mg/mL (217·19 mM; Need ultrasonic)
- InChIKey
- OAZAPIKYVGRNCO-UHFFFAOYSA-N
- Catalogue number
- GC64834
- Brand
- GLPBIO
Computed properties PubChem CID 155595464 · XLogP 4 · TPSA 62.7 Ų · H-bond donors 1
- XLogP
- 4
- TPSA
- 62.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Rotatable bonds
- 5
- Heavy atoms
- 33
SMILES CC(C)(C1=CC=C(C=C1)N2CC3=C(C2=O)C=CN=C3C4=C(C=C(C=C4)F)OCC(F)(F)F)O
Computed descriptors from PubChem (CID 155595464), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il