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Chemical structure of PLX7922

GC64828

PLX7922

Also known as 5-(2-aminopyrimidin-4-yl)-2-tert-butyl-4-[3-[[ethyl(methyl)sulfamoyl]amino]-2-fluorophenyl]-1,3-thiazole

PLX7922, a RAF inhibitor, can bind with BRAFV600E· PLX7922 inhibits pERK in BRAFV600E cell lines, and activates pERK in mutant NRAS cell lines

ChemicalCAS1638772-61-8MW464.58FormulaC20H25FN6O2S2
CAS number
1638772-61-8
Molecular weight
464.58
Formula
C20H25FN6O2S2
Solubility
DMSO ： 100 mg/mL (215·25 mM; Need ultrasonic)
InChIKey
YBUJMZKTOUBMGW-UHFFFAOYSA-N
Catalogue number
GC64828
Brand
GLPBIO
Computed properties PubChem CID 91971376 · XLogP 3.3 · TPSA 151 Ų · H-bond donors 2
XLogP
3.3
TPSA
151 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
31

SMILES CCN(C)S(=O)(=O)NC1=CC=CC(=C1F)C2=C(SC(=N2)C(C)(C)C)C3=NC(=NC=C3)N

Computed descriptors from PubChem (CID 91971376), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.