GC19298
PLX51107
Also known as 4-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1S)-1-pyridin-2-ylethyl]pyrrolo[3,2-b]pyridin-3-yl]benzoic acid
PLX51107 is a potent and selective BET inhibitor, with Kds of 1·6, 2·1, 1·7, and 5 nM for BD1 and 5·9, 6·2, 6·1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively; PLX51107 also interacts with the bromodomains of CBP and EP300 (Kd, in the 100 nM range)
ChemicalCAS1627929-55-8MW438.48FormulaC26H22N4O3
- CAS number
- 1627929-55-8
- Molecular weight
- 438.48
- Formula
- C26H22N4O3
- Solubility
- DMSO ： 75 mg/mL (171·05 mM)
- InChIKey
- AMSUHYUVOVCWTP-INIZCTEOSA-N
- Catalogue number
- GC19298
- Brand
- GLPBIO
Computed properties PubChem CID 90448953 · XLogP 4 · TPSA 94 Ų · H-bond donors 1
- XLogP
- 4
- TPSA
- 94 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Rotatable bonds
- 5
- Heavy atoms
- 33
SMILES CC1=C(C(=NO1)C)C2=CC3=C(C(=CN3[C@@H](C)C4=CC=CC=N4)C5=CC=C(C=C5)C(=O)O)N=C2
Computed descriptors from PubChem (CID 90448953), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il