GC64825
PROTAC HSP90 degrader BP3
Also known as 4-[4-[2-amino-4-chloro-7-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]but-3-ynylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
PROTAC HSP90 degrader BP3 is a potent and selective degradation of HSP90 in a CRBN-dependent fashion· PROTAC HSP90 degrader BP3 has a certain certain degradation effect on HSP90 protein in MCF-7 cells (DC50=0·99 ?M)· PROTAC HSP90 degrader BP3 inhibits the growth of breast cancer cell
ChemicalCAS2669072-88-0MW641.08FormulaC32H29ClN8O5
- CAS number
- 2669072-88-0
- Molecular weight
- 641.08
- Formula
- C32H29ClN8O5
- InChIKey
- ZSERQSKFLSKTGE-UHFFFAOYSA-N
- Catalogue number
- GC64825
- Brand
- GLPBIO
Computed properties PubChem CID 163196223 · XLogP 3.6 · TPSA 174 Ų · H-bond donors 3
- XLogP
- 3.6
- TPSA
- 174 Ų
- H-bond donors
- 3
- H-bond acceptors
- 10
- Rotatable bonds
- 8
- Heavy atoms
- 46
SMILES CC1=CN=C(C(=C1OC)C)CN2C=C(C3=C2N=C(N=C3Cl)N)C#CCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O
Computed descriptors from PubChem (CID 163196223), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il