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Chemical structure of EB-42486

GC64730

EB-42486

Also known as 4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)tetrazolo[1,5-a]pyrimidine-6-carboxamide

EB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50 ＜ 0·2 nM)

ChemicalCAS2390475-81-5MW414.46FormulaC22H22N8O
CAS number
2390475-81-5
Molecular weight
414.46
Formula
C22H22N8O
Solubility
DMSO ： 250 mg/mL (603·19 mM; Need ultrasonic)
InChIKey
KHSAHYKLUPESPP-UHFFFAOYSA-N
Catalogue number
GC64730
Brand
GLPBIO
Computed properties PubChem CID 155925851 · XLogP 2.9 · TPSA 105 Ų · H-bond donors 2
XLogP
2.9
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
31

SMILES CC1=C(C(N2C(=NN=N2)N1C)(C)C)C(=O)NC3=CC4=C(C=C3)NN=C4C5=CC=CC=C5

Computed descriptors from PubChem (CID 155925851), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.