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Chemical structure of EB-3D

GC39377

EB-3D

Also known as 1-[[4-[2-[4-[[4-(dimethylamino)pyridin-1-ium-1-yl]methyl]phenoxy]ethoxy]phenyl]methyl]-N,N-dimethylpyridin-1-ium-4-amine dibromide

EB-3D is a potent and selective choline kinase α (ChoKα) inhibitor, with an IC50 of 1 μM for ChoKα1· EB-3D exerts effects on ChoKα expression, AMPK activation, apoptosis, endoplasmic reticulum stress and lipid metabolism· EB-3D exhibits a potent antiproliferative activity in a panel of T-leukemia cell lines· Anti-cancer activity

ChemicalCAS1839150-63-8MW644.44FormulaC30H36Br2N4O2
CAS number
1839150-63-8
Molecular weight
644.44
Formula
C30H36Br2N4O2
Solubility
DMSO： 50 mg/mL (77·59 mM)
InChIKey
SCXVGPSPZQBBDM-UHFFFAOYSA-L
Catalogue number
GC39377
Brand
GLPBIO
Computed properties PubChem CID 90467110 · TPSA 32.7 Ų · H-bond donors 0 · H-bond acceptors 6
TPSA
32.7 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
11
Heavy atoms
38

SMILES CN(C)C1=CC=[N+](C=C1)CC2=CC=C(C=C2)OCCOC3=CC=C(C=C3)C[N+]4=CC=C(C=C4)N(C)C.[Br-].[Br-]

Computed descriptors from PubChem (CID 90467110), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.