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Chemical structure of GNF2133

GC64724

GNF2133

Also known as 4-ethyl-N-[4-[1-(oxan-4-yl)pyrrolo[2,3-c]pyridin-3-yl]-2-pyridinyl]piperazine-1-carboxamide

GNF2133 is a potent, selective and orally active DYRK1A inhibitor with IC50s of 0·0062, >50 ?M for DYRK1A and GSK3β, respectively

ChemicalCAS2561414-56-8MW434.53FormulaC24H30N6O2
CAS number
2561414-56-8
Molecular weight
434.53
Formula
C24H30N6O2
InChIKey
SAZIAQSVBIWIDU-UHFFFAOYSA-N
Catalogue number
GC64724
Brand
GLPBIO
Computed properties PubChem CID 145994392 · XLogP 1.5 · TPSA 75.5 Ų · H-bond donors 1
XLogP
1.5
TPSA
75.5 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
32

SMILES CCN1CCN(CC1)C(=O)NC2=NC=CC(=C2)C3=CN(C4=C3C=CN=C4)C5CCOCC5

Computed descriptors from PubChem (CID 145994392), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.