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Chemical structure of Thalidomide-Piperazine-Piperidine hydrochloride

GC64640

Thalidomide-Piperazine-Piperidine hydrochloride

Also known as 2-(2,6-dioxopiperidin-3-yl)-5-(4-piperidin-4-ylpiperazin-1-yl)isoindole-1,3-dione;hydrochloride

Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized E3 ligase ligand-linker conjugate· Thalidomide-Piperazine-Piperidine hydrochloride incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology

ChemicalCAS2599846-44-1MW461.94FormulaC22H28ClN5O4
CAS number
2599846-44-1
Molecular weight
461.94
Formula
C22H28ClN5O4
Solubility
Water : 33·33 mg/mL (72·15 mM; Need ultrasonic)|DMSO : 3·6 mg/mL (7·79 mM; ultrasonic and warming and heat to 60°C)
InChIKey
KSERQHVRIGYCSY-UHFFFAOYSA-N
Catalogue number
GC64640
Brand
GLPBIO
Computed properties PubChem CID 162642714 · TPSA 102 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
102 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
32

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)N4CCN(CC4)C5CCNCC5.Cl

Computed descriptors from PubChem (CID 162642714), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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