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Chemical structure of Thalidomide-Piperazine-PEG1-COOH

GC62037

Thalidomide-Piperazine-PEG1-COOH

Also known as 3-[2-[4-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperazin-1-yl]ethoxy]propanoic acid

Thalidomide-Piperazine-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology

ChemicalCAS2731007-11-5MW458.46FormulaC22H26N4O7
CAS number
2731007-11-5
Molecular weight
458.46
Formula
C22H26N4O7
Solubility
DMSO : 250 mg/mL (545·30 mM)
InChIKey
QEXXXOMKDFNBIX-UHFFFAOYSA-N
Catalogue number
GC62037
Brand
GLPBIO
Computed properties PubChem CID 162642713 · XLogP -2.7 · TPSA 137 Ų · H-bond donors 2
XLogP
-2.7
TPSA
137 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
33

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)N4CCN(CC4)CCOCCC(=O)O

Computed descriptors from PubChem (CID 162642713), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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