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Chemical structure of GSK251

GC64612

GSK251

Also known as N-[2-[2-fluoro-4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]-4-pyridinyl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode

ChemicalCAS2125968-05-8MW584.71FormulaC29H37FN6O4S
CAS number
2125968-05-8
Molecular weight
584.71
Formula
C29H37FN6O4S
Solubility
DMSO ： 62·5 mg/mL (106·89 mM; ultrasonic and warming and heat to 60°C)
InChIKey
ODQVPYNCHSLNGV-UHFFFAOYSA-N
Catalogue number
GC64612
Brand
GLPBIO
Computed properties PubChem CID 130302563 · XLogP 2.6 · TPSA 109 Ų · H-bond donors 1
XLogP
2.6
TPSA
109 Ų
H-bond donors
1
H-bond acceptors
11
Rotatable bonds
9
Heavy atoms
41

SMILES CC(C)N1CCN(CC1)CC2=CC(=C(C=C2)C3=NC=CC(=C3)NS(=O)(=O)C4=C(N=CC(=C4)N5CCOCC5)OC)F

Computed descriptors from PubChem (CID 130302563), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.