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Chemical structure of GSK2330672

GC19180

GSK2330672

Also known as 3-[[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-4,5-dihydro-2H-1lambda6,4-benzothiazepin-8-yl]methylamino]pentanedioic acid

GSK2330672 (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium-dependent bile acid transporter (ASBT) inhibitor with an IC50 of 42 nM human ASBT

ChemicalCAS1345982-69-5MW546.68FormulaC28H38N2O7S
CAS number
1345982-69-5
Molecular weight
546.68
Formula
C28H38N2O7S
Solubility
DMSO : 21·5 mg/mL (39·33 mM)
InChIKey
CZGVOBIGEBDYTP-VSGBNLITSA-N
Catalogue number
GC19180
Brand
GLPBIO
Computed properties PubChem CID 53492727 · XLogP -1.6 · TPSA 150 Ų · H-bond donors 4
XLogP
-1.6
TPSA
150 Ų
H-bond donors
4
H-bond acceptors
9
Rotatable bonds
13
Heavy atoms
38

SMILES CCCC[C@@]1(CS(=O)(=O)C2=C(C=C(C(=C2)CNC(CC(=O)O)CC(=O)O)OC)[C@H](N1)C3=CC=CC=C3)CC

Computed descriptors from PubChem (CID 53492727), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.