Loading...
Chemical structure of PARP1-IN-8

GC64578

PARP1-IN-8

Also known as N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2-yl)propanamide

PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 97 nM· PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549

ChemicalCAS836640-15-4MW403.86FormulaC23H18ClN3O2
CAS number
836640-15-4
Molecular weight
403.86
Formula
C23H18ClN3O2
Solubility
DMSO ： 62·5 mg/mL (154·76 mM; Need ultrasonic)
InChIKey
BOYHFRMRSLOWLL-UHFFFAOYSA-N
Catalogue number
GC64578
Brand
GLPBIO
Computed properties PubChem CID 3796800 · XLogP 4.3 · TPSA 61.8 Ų · H-bond donors 1
XLogP
4.3
TPSA
61.8 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
5
Heavy atoms
29

SMILES C1=CC=C(C=C1)C2=NN(C(=O)C3=CC=CC=C32)CCC(=O)NC4=CC(=CC=C4)Cl

Computed descriptors from PubChem (CID 3796800), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.