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Chemical structure of PARP14 inhibitor H10

GC39302

PARP14 inhibitor H10

Also known as 3-[2-[4-[2-[[4-(3-carbamoylanilino)-4-oxobutanoyl]amino]ethyl]triazol-1-yl]ethylsulfamoyl]benzoic acid

PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1)· PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis

ChemicalCAS2084811-68-5MW557.58FormulaC24H27N7O7S
CAS number
2084811-68-5
Molecular weight
557.58
Formula
C24H27N7O7S
Solubility
DMSO: 62·5 mg/mL (112·09 mM)
InChIKey
MUOMSHSMJCWQFH-UHFFFAOYSA-N
Catalogue number
GC39302
Brand
GLPBIO
Computed properties PubChem CID 122707115 · XLogP -1 · TPSA 224 Ų · H-bond donors 5
XLogP
-1
TPSA
224 Ų
H-bond donors
5
H-bond acceptors
10
Rotatable bonds
14
Heavy atoms
39

SMILES C1=CC(=CC(=C1)NC(=O)CCC(=O)NCCC2=CN(N=N2)CCNS(=O)(=O)C3=CC=CC(=C3)C(=O)O)C(=O)N

Computed descriptors from PubChem (CID 122707115), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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