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Chemical structure of PF-04745637

GC64573

PF-04745637

Also known as 1-(4-chlorophenyl)-N-[(2R)-2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]-3-phenylpropyl]cyclopentane-1-carboxamide

PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1

ChemicalCAS1917294-46-2MW509FormulaC27H32ClF3N2O2
CAS number
1917294-46-2
Molecular weight
509
Formula
C27H32ClF3N2O2
Solubility
DMSO : 100 mg/mL (196·46 mM; Need ultrasonic)
InChIKey
PAEBEJVPSADOMC-HSZRJFAPSA-N
Catalogue number
GC64573
Brand
GLPBIO
Computed properties PubChem CID 121304827 · XLogP 6.1 · TPSA 52.6 Ų · H-bond donors 2
XLogP
6.1
TPSA
52.6 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
35

SMILES C1CCC(C1)(C2=CC=C(C=C2)Cl)C(=O)NC[C@@H](CC3=CC=CC=C3)N4CCC(CC4)(C(F)(F)F)O

Computed descriptors from PubChem (CID 121304827), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.