Loading...
Chemical structure of PF-04856264

GC61174

PF-04856264

Also known as 3-cyano-4-[2-(2-methylpyrazol-3-yl)phenoxy]-N-(1,3-thiazol-2-yl)benzenesulfonamide

PF-04856264 is a potent and selective Nav1·7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1·7, respectively

ChemicalCAS1235397-05-3MW437.49FormulaC20H15N5O3S2
CAS number
1235397-05-3
Molecular weight
437.49
Formula
C20H15N5O3S2
Solubility
DMSO ： 250 mg/mL (571·44 mM; ultrasonic and warming and heat to 60°C)
InChIKey
MKSKJVIBSRUWSZ-UHFFFAOYSA-N
Catalogue number
GC61174
Brand
GLPBIO
Computed properties PubChem CID 71718072 · XLogP 3 · TPSA 147 Ų · H-bond donors 1
XLogP
3
TPSA
147 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
30

SMILES CN1C(=CC=N1)C2=CC=CC=C2OC3=C(C=C(C=C3)S(=O)(=O)NC4=NC=CS4)C#N

Computed descriptors from PubChem (CID 71718072), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.