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Chemical structure of ML198

GC64507

ML198

Also known as N-(4-ethynylphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide

ML198 is a glucocerebrosidase (GCase) modulator with an EC50 of 0·4 μM

ChemicalCAS1380716-06-2MW290.32FormulaC17H14N4O
CAS number
1380716-06-2
Molecular weight
290.32
Formula
C17H14N4O
Solubility
DMSO ： 5 mg/mL (17·22 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)
InChIKey
HVZPJBKUFRREQC-UHFFFAOYSA-N
Catalogue number
GC64507
Brand
GLPBIO
Computed properties PubChem CID 46907762 · XLogP 2.2 · TPSA 59.3 Ų · H-bond donors 1
XLogP
2.2
TPSA
59.3 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
22

SMILES CC1=CC(=NC2=C(C=NN12)C(=O)NC3=CC=C(C=C3)C#C)C

Computed descriptors from PubChem (CID 46907762), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
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