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Chemical structure of RUVBL1/2 ATPase-IN-1

GC64439

RUVBL1/2 ATPase-IN-1

Also known as [5,7-dimethyl-6-[(4-methylphenyl)methyl]pyrazolo[1,5-a]pyrimidin-3-yl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone

RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6·0 and 7·7 μM, respectively· RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer· RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases

ChemicalCAS423128-55-6MW507.55FormulaC28H28F3N5O
CAS number
423128-55-6
Molecular weight
507.55
Formula
C28H28F3N5O
Solubility
DMSO ： 10 mg/mL (19·70 mM; ultrasonic and warming and heat to 60°C)
InChIKey
DWMRUZCWNNNCJM-UHFFFAOYSA-N
Catalogue number
GC64439
Brand
GLPBIO
Computed properties PubChem CID 4103510 · XLogP 5.3 · TPSA 53.7 Ų · H-bond donors 0
XLogP
5.3
TPSA
53.7 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
37

SMILES CC1=CC=C(C=C1)CC2=C(N3C(=C(C=N3)C(=O)N4CCN(CC4)C5=CC=CC(=C5)C(F)(F)F)N=C2C)C

Computed descriptors from PubChem (CID 4103510), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.