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Chemical structure of SGC-CK2-1

GC64382

SGC-CK2-1

Also known as N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]propanamide

SGC-CK2-1 is a highly potent, ATP-competitive, and cell-active CK2 chemical probe with exclusive selectivity for both human CK2 isoforms, with IC50s of 36 and 16 nM for CK2α and CK2α′respectively in the nanoBRET assay

ChemicalCAS2470424-39-4MW375.43FormulaC20H21N7O
CAS number
2470424-39-4
Molecular weight
375.43
Formula
C20H21N7O
Solubility
DMSO ： 100 mg/mL (266·36 mM; Need ultrasonic)
InChIKey
YKDZIFFKQUNVHH-UHFFFAOYSA-N
Catalogue number
GC64382
Brand
GLPBIO
Computed properties PubChem CID 146681133 · XLogP 2.8 · TPSA 107 Ų · H-bond donors 3
XLogP
2.8
TPSA
107 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
28

SMILES CCC(=O)NC1=C(C=CC(=C1)NC2=NC3=C(C=NN3C(=C2)NC4CC4)C#N)C

Computed descriptors from PubChem (CID 146681133), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.