GC64238
KIRA-7
Also known as 1-[4-[8-amino-3-(1-methylcyclopropyl)imidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl]-3-(3-fluorophenyl)urea
KIRA-7, an imidazopyrazine compound, binds the IRE1α kinase (IC50 of 110 nM) to allosterically inhibit its RNase activity
ChemicalCAS1937235-76-1MW466.51FormulaC27H23FN6O
- CAS number
- 1937235-76-1
- Molecular weight
- 466.51
- Formula
- C27H23FN6O
- Solubility
- DMSO ： 100 mg/mL (214·36 mM; Need ultrasonic)
- InChIKey
- BMEJPYIGRYVVEF-UHFFFAOYSA-N
- Catalogue number
- GC64238
- Brand
- GLPBIO
Computed properties PubChem CID 121596794 · XLogP 5.1 · TPSA 97.3 Ų · H-bond donors 3
- XLogP
- 5.1
- TPSA
- 97.3 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 35
SMILES CC1(CC1)C2=NC(=C3N2C=CN=C3N)C4=CC=C(C5=CC=CC=C54)NC(=O)NC6=CC(=CC=C6)F
Computed descriptors from PubChem (CID 121596794), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il