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Chemical structure of Befotertinib

GC64017

Befotertinib

Also known as N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-[1-(2,2,2-trifluoroethyl)indol-3-yl]pyrimidin-2-yl]amino]phenyl]prop-2-enamide

Befotertinib (D-0316) is the third-generation EGFR tyrosine kinase inhibitor· Befotertinib can be used for the research of EGFR T790M-positive non-small cell lung cancer (NSCLC)

ChemicalCAS1835667-63-4MW567.61FormulaC29H32F3N7O2
CAS number
1835667-63-4
Molecular weight
567.61
Formula
C29H32F3N7O2
Solubility
DMSO : 62·5 mg/mL (110·11 mM; ultrasonic and warming and heat to 60°C)
InChIKey
USOCZVZOXKTJTI-UHFFFAOYSA-N
Catalogue number
GC64017
Brand
GLPBIO
Computed properties PubChem CID 130412842 · XLogP 4.8 · TPSA 87.6 Ų · H-bond donors 2
XLogP
4.8
TPSA
87.6 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
11
Heavy atoms
41

SMILES CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)CC(F)(F)F)OC

Computed descriptors from PubChem (CID 130412842), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.