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Chemical structure of Begacestat

GC12659

Begacestat

Also known as 5-chloro-N-[(2S)-4,4,4-trifluoro-1-hydroxy-3-(trifluoromethyl)butan-2-yl]thiophene-2-sulfonamide

An inhibitor of γ-secretase

ChemicalCAS769169-27-9MW391.74FormulaC9H8ClF6NO3S2
CAS number
769169-27-9
Molecular weight
391.74
Formula
C9H8ClF6NO3S2
Solubility
＜39·17mg/ml in DMSO; ＜39·17mg/ml in ethanol
InChIKey
PSXOKXJMVRSARX-SCSAIBSYSA-N
Catalogue number
GC12659
Brand
GLPBIO
Computed properties PubChem CID 11269353 · XLogP 3.7 · TPSA 103 Ų · H-bond donors 2
XLogP
3.7
TPSA
103 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
5
Heavy atoms
22

SMILES C1=C(SC(=C1)Cl)S(=O)(=O)N[C@H](CO)C(C(F)(F)F)C(F)(F)F

Computed descriptors from PubChem (CID 11269353), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.