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Chemical structure of BLU-945

GC63910

BLU-945

Also known as N-[2-[(3S,4R)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl]-8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-amine

BLU-945 is a potent, highly selective, reversible and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)

ChemicalCAS2660250-10-0MW556.7FormulaC28H37FN6O3S
CAS number
2660250-10-0
Molecular weight
556.7
Formula
C28H37FN6O3S
InChIKey
LIMFPAAAIVQRRD-BCGVJQADSA-N
Catalogue number
GC63910
Brand
GLPBIO
Computed properties PubChem CID 156538665 · XLogP 4.6 · TPSA 109 Ų · H-bond donors 1
XLogP
4.6
TPSA
109 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
8
Heavy atoms
39

SMILES C[C@@H]1[C@H](CN1C2=C3C=NC(=CC3=C(C=C2)C(C)C)NC4=NC(=NC=C4)N5CC[C@H]([C@H](C5)F)OC)CS(=O)(=O)C

Computed descriptors from PubChem (CID 156538665), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.