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Chemical structure of Thalidomide-5-NH2-CH2-COOH

GC63810

Thalidomide-5-NH2-CH2-COOH

Also known as 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]acetic acid

Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk)

ChemicalCAS2412056-27-8MW331.28FormulaC15H13N3O6
CAS number
2412056-27-8
Molecular weight
331.28
Formula
C15H13N3O6
Solubility
DMSO : 33·33 mg/mL (100·61 mM; Need ultrasonic)
InChIKey
ZATMCTCUKSYXHM-UHFFFAOYSA-N
Catalogue number
GC63810
Brand
GLPBIO
Computed properties PubChem CID 146410371 · XLogP -0.1 · TPSA 133 Ų · H-bond donors 3
XLogP
-0.1
TPSA
133 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
24

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)NCC(=O)O

Computed descriptors from PubChem (CID 146410371), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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