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Chemical structure of Lenalidomide-5-aminomethyl hydrochloride

GC63806

Lenalidomide-5-aminomethyl hydrochloride

Also known as 3-[6-(aminomethyl)-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione;hydrochloride

Lenalidomide-5-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein· Lenalidomide-5-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC

ChemicalCAS1158264-69-7MW309.75FormulaC14H16ClN3O3
CAS number
1158264-69-7
Molecular weight
309.75
Formula
C14H16ClN3O3
Solubility
DMSO : 16·67 mg/mL (53·82 mM; ultrasonic and warming and heat to 60°C)
InChIKey
XTILEMYXOZKSFJ-UHFFFAOYSA-N
Catalogue number
GC63806
Brand
GLPBIO
Computed properties PubChem CID 66589525 · TPSA 92.5 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
92.5 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
21

SMILES C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC(=C3)CN.Cl

Computed descriptors from PubChem (CID 66589525), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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