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Chemical structure of BRD0639

GC63731

BRD0639

Also known as (2S)-2-(4-chloro-6-oxopyridazin-1-yl)-N-[4-methyl-3-(2-pyridin-2-ylethylsulfamoyl)phenyl]propanamide

BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction· BRD0639 is a PRMT5 binding motif (PBM)-competitive agent that can support studies of PBM dependent PRMT5 activities

ChemicalCAS2760881-74-9MW475.95FormulaC21H22ClN5O4S
CAS number
2760881-74-9
Molecular weight
475.95
Formula
C21H22ClN5O4S
Solubility
DMSO ： 250 mg/mL (525·27 mM; Need ultrasonic)
InChIKey
BXDCFRRDENJUJM-HNNXBMFYSA-N
Catalogue number
GC63731
Brand
GLPBIO
Computed properties PubChem CID 156621384 · XLogP 1.9 · TPSA 129 Ų · H-bond donors 2
XLogP
1.9
TPSA
129 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
32

SMILES CC1=C(C=C(C=C1)NC(=O)[C@H](C)N2C(=O)C=C(C=N2)Cl)S(=O)(=O)NCCC3=CC=CC=N3

Computed descriptors from PubChem (CID 156621384), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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