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Chemical structure of DCLX069

GC63662

DCLX069

Also known as ethyl 3-amino-4-(4-benzylpiperazin-1-yl)benzoate

DCLX069 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 value of 17·9 ?M· DCLX069 shows less active against PRMT4 and PRMT6· DCLX069 has anticancer effects

ChemicalCAS792946-69-1MW339.43FormulaC20H25N3O2
CAS number
792946-69-1
Molecular weight
339.43
Formula
C20H25N3O2
InChIKey
RITRCMIWRZBDID-UHFFFAOYSA-N
Catalogue number
GC63662
Brand
GLPBIO
Computed properties PubChem CID 2997002 · XLogP 2.9 · TPSA 58.8 Ų · H-bond donors 1
XLogP
2.9
TPSA
58.8 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
25

SMILES CCOC(=O)C1=CC(=C(C=C1)N2CCN(CC2)CC3=CC=CC=C3)N

Computed descriptors from PubChem (CID 2997002), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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