GC39486
DCLK1-IN-1
Also known as 2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-11-methyl-5-(2,2,2-trifluoroethyl)pyrimido[4,5-b][1,4]benzodiazepin-6-one
DCLK1-IN-1 is a highly selective inhibitor of DCLK1 and DCLK2 with IC50 values of 9·5nM and 31nM respectively in the KINOMEscan binding assay, and IC50 values of 57nM and 103nM respectively in the ATP kinase assay
ChemicalCAS2222635-15-4MW527.54FormulaC26H28F3N7O2
- CAS number
- 2222635-15-4
- Molecular weight
- 527.54
- Formula
- C26H28F3N7O2
- Solubility
- DMSO： 35·71 mg/mL (67·69 mM)
- InChIKey
- OQFCHSFVWSLDAO-UHFFFAOYSA-N
- Catalogue number
- GC39486
- Brand
- GLPBIO
Computed properties PubChem CID 134457640 · XLogP 4.2 · TPSA 77.1 Ų · H-bond donors 1
- XLogP
- 4.2
- TPSA
- 77.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 11
- Rotatable bonds
- 5
- Heavy atoms
- 38
SMILES CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C5=CC=CC=C5C(=O)N4CC(F)(F)F)C)OC
Computed descriptors from PubChem (CID 134457640), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il