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Chemical structure of ZW4864 free base

GC63559

ZW4864 free base

Also known as (3R)-N-cyclopropyl-1-[3-(2-methyl-1-oxo-1-piperazin-1-ylpropan-2-yl)oxyphenyl]-N-[[4-(1H-pyrazol-4-yl)phenyl]methyl]piperidine-3-carboxamide

ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein?protein interaction (β catenin/BCL9 PPI) inhibitor· ZW4864 (free base) inhibits β catenin/BCL9 PPI with a Ki value of 0·76 μM and an IC50 value of 0·87 μM

ChemicalCAS2632259-92-6MW570.72FormulaC33H42N6O3
CAS number
2632259-92-6
Molecular weight
570.72
Formula
C33H42N6O3
InChIKey
DEGJSKLSOCKWSF-AREMUKBSSA-N
Catalogue number
GC63559
Brand
GLPBIO
Computed properties PubChem CID 156180089 · XLogP 3.4 · TPSA 93.8 Ų · H-bond donors 2
XLogP
3.4
TPSA
93.8 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
42

SMILES CC(C)(C(=O)N1CCNCC1)OC2=CC=CC(=C2)N3CCC[C@H](C3)C(=O)N(CC4=CC=C(C=C4)C5=CNN=C5)C6CC6

Computed descriptors from PubChem (CID 156180089), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.