GC37973
ZT-12-037-01
Also known as 2-N-cyclopropyl-6,7-dimethoxy-4-N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine
ZT-12-037-01 is a STK19-targeted inhibitor, has a high-affinity interaction with STK19 protein and inhibits oncogenic NRAS-driven melanocyte malignant transformation· ZT-12-037-01 is an ATP-competitive inhibitor, inhibiting phosphorylation of NRAS (major isoform of Ras family) with an IC50 of 24 nM
ChemicalCAS2328073-61-4MW385.5FormulaC21H31N5O2
- CAS number
- 2328073-61-4
- Molecular weight
- 385.5
- Formula
- C21H31N5O2
- Solubility
- DMSO： 8·33 mg/mL (21·61 mM)
- InChIKey
- AMAQJTHMSLYMFT-UHFFFAOYSA-N
- Catalogue number
- GC37973
- Brand
- GLPBIO
Computed properties PubChem CID 138911316 · XLogP 4.1 · TPSA 71.5 Ų · H-bond donors 2
- XLogP
- 4.1
- TPSA
- 71.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 7
- Heavy atoms
- 28
SMILES CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)NC4CC4
Computed descriptors from PubChem (CID 138911316), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il