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Chemical structure of PROTAC CBP/P300 Degrader-1

GC63544

PROTAC CBP/P300 Degrader-1

Also known as 3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-[1-[6-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]hexanoyl]piperidin-4-yl]-N-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide

PROTAC CBP/P300 Degrader-1 is a potent PROTAC CBP/P300 degrader· PROTAC CBP/P300 Degrader-1 potently inhibited cell viability of multiple cancer cell lines

ChemicalCAS2484739-48-0MW893.98FormulaC46H53F2N11O6
CAS number
2484739-48-0
Molecular weight
893.98
Formula
C46H53F2N11O6
Solubility
DMSO ： 173·33 mg/mL (193·89 mM; Need ultrasonic)
InChIKey
KOXRGDZBEAJAKE-UHFFFAOYSA-N
Catalogue number
GC63544
Brand
GLPBIO
Computed properties PubChem CID 162642580 · XLogP 3.8 · TPSA 187 Ų · H-bond donors 3
XLogP
3.8
TPSA
187 Ų
H-bond donors
3
H-bond acceptors
12
Rotatable bonds
12
Heavy atoms
65

SMILES CNC(=O)N1CCC2=C(C1)C(=NN2C3CCN(CC3)C(=O)CCCCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)N7CCCC8=CC(=C(C=C87)C(F)F)C9=CN(N=C9)C

Computed descriptors from PubChem (CID 162642580), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.