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Chemical structure of Lenalidomide-C5-amido-Boc

GC63474

Lenalidomide-C5-amido-Boc

Also known as tert-butyl N-[5-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]pentyl]carbamate

Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein· Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC

ChemicalCAS2138441-25-3MW429.51FormulaC23H31N3O5
CAS number
2138441-25-3
Molecular weight
429.51
Formula
C23H31N3O5
InChIKey
HEDNUGMKVBGPTI-UHFFFAOYSA-N
Catalogue number
GC63474
Brand
GLPBIO
Computed properties PubChem CID 145926837 · XLogP 2.4 · TPSA 105 Ų · H-bond donors 2
XLogP
2.4
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
9
Heavy atoms
31

SMILES CC(C)(C)OC(=O)NCCCCCC1=C2CN(C(=O)C2=CC=C1)C3CCC(=O)NC3=O

Computed descriptors from PubChem (CID 145926837), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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