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Chemical structure of TAK-418

GC63437

TAK-418

Also known as 5-[(1R,2R)-2-(cyclopropylmethylamino)cyclopropyl]-N-(oxan-4-yl)thiophene-3-carboxamide;hydrochloride

TAK-418 is a selective, orally active LSD1 (KDM1A) enzyme inhibitor with an IC50 of 2·9 nM

ChemicalCAS1818252-53-7MW356.91FormulaC17H25ClN2O2S
CAS number
1818252-53-7
Molecular weight
356.91
Formula
C17H25ClN2O2S
Solubility
DMSO ： 55 mg/mL (154·10 mM; ultrasonic and warming and heat to 60°C); H2O ： ≥ 16·67 mg/mL (46·71 mM)
InChIKey
LEEWMGOHGNRDKC-CTHHTMFSSA-N
Catalogue number
GC63437
Brand
GLPBIO
Computed properties PubChem CID 118432651 · TPSA 78.6 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
78.6 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
23

SMILES C1CC1CN[C@@H]2C[C@H]2C3=CC(=CS3)C(=O)NC4CCOCC4.Cl

Computed descriptors from PubChem (CID 118432651), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.