Loading...
Chemical structure of TAK 259

GB40382

TAK 259

Also known as 5-chloro-1-[(5-chloro-2-methylsulfonylphenyl)methyl]-2-iminopyridine-3-carboxamide;hydrochloride

Novel, selective, and orally active α1D adrenoceptor antagonist (Ki value 1·1 nM, and 200-800 fold selective over α1A and α1B, respectively) with anti-urinary frequency effects: reducing human Ether-a-go-go-Related Gene (hERG) liabilities· Clinical candidate, and a promising novel therapeutic agent for the treatment of OAB (overactive bladder) symptoms

ChemicalCAS1192347-42-4MW410.7FormulaC14H13Cl2N3O3S·HCl
CAS number
1192347-42-4
Molecular weight
410.7
Formula
C14H13Cl2N3O3S·HCl
InChIKey
MWQYDDZQXFWUAN-UHFFFAOYSA-N
Catalogue number
GB40382
Brand
GLPBIO
Computed properties PubChem CID 66970086 · TPSA 113 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
113 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
24

SMILES CS(=O)(=O)C1=C(C=C(C=C1)Cl)CN2C=C(C=C(C2=N)C(=O)N)Cl.Cl

Computed descriptors from PubChem (CID 66970086), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.