GC63354
Intoplicine dimesylate
Also known as 16-[3-(dimethylamino)propylamino]-13-methyl-11,15-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-1(10),2(7),3,5,8,12(17),13,15-octaen-5-ol;methanesulfonic acid
Intoplicine (RP 60475) dimesylate, an antitumor derivative in the 7H-benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase I and II inhibitor· Intoplicine dimesylate strongly binds DNA (KA = 2 x 105 /M) and thereby increases the length of linear DNA
ChemicalCAS133711-99-6MW540.65FormulaC23H32N4O7S2
- CAS number
- 133711-99-6
- Molecular weight
- 540.65
- Formula
- C23H32N4O7S2
- Solubility
- DMSO ： 115 mg/mL (212·71 mM; Need ultrasonic)
- InChIKey
- JAUYMMJDKJISLX-UHFFFAOYSA-N
- Catalogue number
- GC63354
- Brand
- GLPBIO
Computed properties PubChem CID 3086634 · TPSA 190 Ų · H-bond donors 5 · H-bond acceptors 10
- TPSA
- 190 Ų
- H-bond donors
- 5
- H-bond acceptors
- 10
- Rotatable bonds
- 5
- Heavy atoms
- 36
SMILES CC1=CN=C(C2=C1NC3=C2C4=C(C=C3)C=C(C=C4)O)NCCCN(C)C.CS(=O)(=O)O.CS(=O)(=O)O
Computed descriptors from PubChem (CID 3086634), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il