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Chemical structure of AWL-II-38·3

GC63301

AWL-II-38·3

Also known as N-[2-methyl-5-[[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)benzoyl]amino]phenyl]-1,2-oxazole-5-carboxamide

AWL-II-38·3 is a potent ephrin-A receptor (EphA3) kinase inhibitor· AWL-II-38·3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf

ChemicalCAS1135205-94-5MW469.42FormulaC23H18F3N5O3
CAS number
1135205-94-5
Molecular weight
469.42
Formula
C23H18F3N5O3
Solubility
DMSO : 66·67 mg/mL (142·03 mM; Need ultrasonic)
InChIKey
IYUFHBXMTTXZBE-UHFFFAOYSA-N
Catalogue number
GC63301
Brand
GLPBIO
Computed properties PubChem CID 24880028 · XLogP 3.8 · TPSA 102 Ų · H-bond donors 2
XLogP
3.8
TPSA
102 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
34

SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC(=O)C4=CC=NO4

Computed descriptors from PubChem (CID 24880028), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Lead time
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Pricing
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Documents
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