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Chemical structure of Zapnometinib

GC63264

Zapnometinib

Also known as 2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid

Zapnometinib (PD0184264), an active metabolite of CI-1040, is a MEK inhibitor, with an IC50 of 5·7 nM

ChemicalCAS303175-44-2MW409.55FormulaC13H7ClF2INO2
CAS number
303175-44-2
Molecular weight
409.55
Formula
C13H7ClF2INO2
Solubility
DMSO ： 62·5 mg/mL (152·61 mM; Need ultrasonic)
InChIKey
XCNBGWKQXRQKSA-UHFFFAOYSA-N
Catalogue number
GC63264
Brand
GLPBIO
Computed properties PubChem CID 10112191 · XLogP 5 · TPSA 49.3 Ų · H-bond donors 2
XLogP
5
TPSA
49.3 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
20

SMILES C1=CC(=C(C=C1I)Cl)NC2=C(C=CC(=C2F)F)C(=O)O

Computed descriptors from PubChem (CID 10112191), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.