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Chemical structure of VU0453595

GC63258

VU0453595

Also known as 6-[[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]methyl]-7H-pyrrolo[3,4-b]pyridin-5-one

VU0453595 is a highly selective, systemically active M1 positive allosteric modulator (PAM, EC50=2140?nM) for the research of schizophrenia

ChemicalCAS1432436-13-9MW322.34FormulaC18H15FN4O
CAS number
1432436-13-9
Molecular weight
322.34
Formula
C18H15FN4O
Solubility
DMSO ： 100 mg/mL (310·23 mM; Need ultrasonic)
InChIKey
LIZQOZALTSDKFU-UHFFFAOYSA-N
Catalogue number
GC63258
Brand
GLPBIO
Computed properties PubChem CID 71555066 · XLogP 1.5 · TPSA 51 Ų · H-bond donors 0
XLogP
1.5
TPSA
51 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
24

SMILES CN1C=C(C=N1)C2=CC(=C(C=C2)CN3CC4=C(C3=O)C=CC=N4)F

Computed descriptors from PubChem (CID 71555066), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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