GC63256
VRT-043198
Also known as (3S)-3-[[(2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoic acid
VRT-043198, the drug metabolite of VX-765 (Belnacasan), is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases
ChemicalCAS244133-31-1MW480.94FormulaC22H29ClN4O6
- CAS number
- 244133-31-1
- Molecular weight
- 480.94
- Formula
- C22H29ClN4O6
- Solubility
- DMSO ： 180 mg/mL (374·27 mM; Need ultrasonic)|Methanol ： 12·5 mg/mL (25·99 mM; Need ultrasonic)
- InChIKey
- SOZONDBMOYWSRW-QANKJYHBSA-N
- Catalogue number
- GC63256
- Brand
- GLPBIO
Computed properties PubChem CID 11443029 · XLogP 1.4 · TPSA 159 Ų · H-bond donors 4
- XLogP
- 1.4
- TPSA
- 159 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Rotatable bonds
- 9
- Heavy atoms
- 33
SMILES CC(C)(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)C2=CC(=C(C=C2)N)Cl
Computed descriptors from PubChem (CID 11443029), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il