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Chemical structure of TAK-915

GC63209

TAK-915

Also known as N-[(1S)-1-[3-fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl]-7-methoxy-2-oxo-1,3-dihydropyrido[2,3-b]pyrazine-4-carboxamide

TAK-915 is a potent, selective, brain-penetrant and orally active phosphodiesterase 2A (PDE2A) inhibitor with an IC50 of 0·61 nM

ChemicalCAS1476727-50-0MW458.36FormulaC19H18F4N4O5
CAS number
1476727-50-0
Molecular weight
458.36
Formula
C19H18F4N4O5
Solubility
DMSO ： 7·5 mg/mL (16·36 mM; ultrasonic and warming and heat to 60°C)
InChIKey
AWJSRXUQLSPAOI-CQSZACIVSA-N
Catalogue number
GC63209
Brand
GLPBIO
Computed properties PubChem CID 72190879 · XLogP 2 · TPSA 102 Ų · H-bond donors 2
XLogP
2
TPSA
102 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
6
Heavy atoms
32

SMILES COC[C@H](C1=CC(=C(C=C1)OC(F)(F)F)F)NC(=O)N2CC(=O)NC3=C2N=CC(=C3)OC

Computed descriptors from PubChem (CID 72190879), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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