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Chemical structure of SAR502250

GC63181

SAR502250

Also known as 2-[(2S)-2-(4-fluorophenyl)morpholin-4-yl]-3-methyl-6-pyrimidin-4-ylpyrimidin-4-one

SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β

ChemicalCAS503860-57-9MW367.38FormulaC19H18FN5O2
CAS number
503860-57-9
Molecular weight
367.38
Formula
C19H18FN5O2
Solubility
DMSO ： 100 mg/mL (272·20 mM; Need ultrasonic)
InChIKey
NKUNFNVAHJNALA-QGZVFWFLSA-N
Catalogue number
GC63181
Brand
GLPBIO
Computed properties PubChem CID 56589672 · XLogP 0.7 · TPSA 70.9 Ų · H-bond donors 0
XLogP
0.7
TPSA
70.9 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
27

SMILES CN1C(=O)C=C(N=C1N2CCO[C@H](C2)C3=CC=C(C=C3)F)C4=NC=NC=C4

Computed descriptors from PubChem (CID 56589672), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.